Clinical manifestation of Swyer syndrome

Women with Swyer's syndrome or pure gonadal dysgenesis XY are characterized by having external female genitalia, rudimentary gonads, a hypoplastic uterus and no secondary sexual characteristics. In addition, these women lack ovaries, so they do not produce sex hormones and present amenorrhea, the main symptom for which they go to the doctor. The absence of ovaries causes female infertility, so the only option to achieve a pregnancy is to resort to egg donation.

Women with Swyer syndrome are usually tall and often have a larger clitoris than other women.