Yes, the success of the assisted reproduction treatment can be compromised if the injection of hCG is administered the wrong way or at the wrong time.
This injection is the last one before the ovarian puncture and is administered, 36 hours before the punction. Its administration promotes a high peak in the LH hormone that helps the oocytes mature and release 38 - 40 hours after its administration, the release is undesirable and must be prevented.
An error in the time of the administration can prevent the oocytes to be retrieved, this can be caused by a False Empty Follicle Syndrome or that the patient has already ovulated.
Read the full article on: What is Empty Follicle Syndrome and ways to prevent it. ( 40).
Laura Parra Villar
Graduate in Biology from the University of Valencia (UV) and embryologist with a Master's degree in Biotechnology of Human Reproduction from the University of Valencia in collaboration with the Valencian Institute of Infertility (IVI).
Licence number: 3325-CV