Yes, it is possible. Secretory azoospermia is the absence of spermatozoa in the ejaculate. When we refer to secretory azoospermia it is when this absence is due to the lack of sperm production in the testicles (spermatogenesis). This sperm alteration can be reversible or irreversible.
In the case of obstruction of the vas deferens it is possible to recover spermatozoa by testicular biopsy so that the male germ cells can be rescued and an ICSI (Intracytoplasmic Sperm Injection) can be performed.