Certified Medical Magazine by WMA, ACSA, HON
FAQs
12
0
Menu

What are the consequences of refractory endometrium?

By Paula Fabra Roca M.D., M.Sc. (gynecologist).
Last Update: 11/29/2021

We speak of refractory endometrium when, in spite of a correct endometrial preparation, this endometrium does not acquire the size and thickness necessary to have a good guarantee of pregnancy.

In these cases the implantation rate, the clinical gestation rate and the live birth rate are reduced. An increase in the rate of miscarriage has not been observed.

When faced with a woman with a refractory endometrium, we must take two approaches. First, perform a hysteroscopy to try to find the cause of the endometrium not growing sufficiently and correct it.

On the other hand, changing the endometrial preparation strategy can also be of great help. Not all endometria respond equally to all estrogens. Some endometrium responds better to a different route of administration (for example, changing the patches for pills), or to a higher dose of estrogens (increasing the dose always within the safe doses), or to the estrogens specific to the woman's cycle (using the natural ovarian cycle instead of giving estrogens externally), etc.

 Paula Fabra Roca
Paula Fabra Roca
M.D., M.Sc.
Gynecologist
Dr. Paula Fabra has a degree in Medicine and Surgery and specializes in Obstetrics and Gynecology. She also has a Master's degree in Assisted Human Reproduction.
collegiate number: 51123
Gynecologist. Dr. Paula Fabra has a degree in Medicine and Surgery and specializes in Obstetrics and Gynecology. She also has a Master's degree in Assisted Human Reproduction. collegiate number: 51123.