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What are the symptoms of Empty Follicle Syndrome?

By Laura Parra Villar B.Sc., M.Sc. (embryologin).
Last Update: 10/19/2021

Empty Follicle Syndrome (EFS) has no symptoms. Therefore it´s frustrating for specialists as well as for patients, as EFS is not diagnosed during the ovarian stimulation phase, it can only be diagnosed after performing the ovarian puncture and not obtaining any oocytes.

However, a series of measures can be taken into account to prevent this in recurring patients: making sure the patient has understood the hormonal treatment administration instructions, increase the dose of hCG, change the stimulation protocols, or suction repeatedly the same follicle.

 Laura Parra Villar
Laura Parra Villar
B.Sc., M.Sc.
Embryologin
Graduate in Biology from the University of Valencia (UV) and embryologist with a Master's degree in Biotechnology of Human Reproduction from the University of Valencia in collaboration with the Valencian Institute of Infertility (IVI).
Licence number: 3325-CV
Embryologin. Graduate in Biology from the University of Valencia (UV) and embryologist with a Master's degree in Biotechnology of Human Reproduction from the University of Valencia in collaboration with the Valencian Institute of Infertility (IVI). Licence number: 3325-CV.