When one of the parents is affected by an autosomal dominant disease, the likelihood of transmitting it to offspring is 50%. For this reason, this group of diseases is one of the main indictions for performing a PGD (Preimplantation Genetic Diagnosis).
Autosomal dominant inheritance pattern
By Dra. Alicia Francos Pérez MD, MSc (gynecologist), Antonio Alcaide Raya BSc, MSc, PhD (senior embryologist), Dra. Victoria Rey Caballero MD, MSc (gynecologist), Zaira Salvador BSc, MSc (embryologist) and Sandra Fernández BA, MA (fertility counselor).
Last Update: 11/08/2018