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Transmission of autosomal recessive diseases
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Transmission of autosomal recessive diseases

Genetic diseases of autosomal recessive inheritance develop when the child inherits two copies of the gene causing the disease in both parents, who can be sick or carriers of the disease if they have just one copy affected.

The probability of transmitting an autosomal recessive disease to offspring if both parents are carriers is 25%, since the child has to inherit both alleles altered to manifest the pathology. On the other hand, the chances for the child to be a carrier are 50%, though.

By BSc, MSc, PhD (senior embryologist), BSc, MSc (embryologist) and BA, MA (fertility counselor).
Last Update: 11/12/2018
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