Like any other hormonal medication, Evopad can cause adverse effects in patients after administration.
Among the most common side effects are headaches, irritation at the patch application site, and breast tenderness. Other relatively common reactions, though less frequent, include lower back pain and irregular vaginal bleeding.
In rare cases, Evopad may cause abdominal pain or diarrhea after being applied to the skin.
Read the full article on: What Is the Role of Estradiol Patches in IVF? ( 72).
By Cristina Mestre Ferrer B.Sc., M.Sc. (embryologist), Esther Marbán Bermejo M.D. (gynecologist), Marta Barranquero Gómez B.Sc., M.Sc. (embryologist), Victoria Moliner BSc, MSc (embryologist) and Romina Packan (invitra staff).
Last Update: 10/13/2025
