The embryo implants in the endometrium approximately 6-8 days after fertilization, when it is already in the blastocyst stage and has detached from its zona pellucida.
In order to do this, there must be a suitable environment in the uterus, i.e. the endometrium must be receptive and in sync with the blastocyst. At this point, a dialogue is established between the two that allows the beginning of embryonic nesting.
This interaction takes place in the four phases of the process (precontact, apposition, adhesion and invasion) through different mediating molecules, such as cytokines, growth factors, integrins and other adhesion molecules, so that the embryo can finally penetrate the maternal endometrium.
Read the full article on: What is embryo implantation and when does it occur? ( 44).
By Antonio Forgiarini M.D., M.Sc. (gynecologist), Blanca Paraíso M.D., Ph.D., M.Sc. (gynecologist), Manuel Muñoz M.D., Ph.D. (gynecologist), Sara Salgado B.Sc., M.Sc. (embryologist), Silvia Jiménez Bravo B.Sc., Ph.D. (senior clinical embryologist), Zaira Salvador B.Sc., M.Sc. (embryologist) and Cristina Algarra Goosman B.Sc., M.Sc. (psychologist).
Last Update: 10/02/2019
