In order to perform an ERA test and study the genes that are expressed in the endometrium of each woman, it is necessary to perform an endometrial biopsy, which consists of extracting a small sample of endometrial tissue through a fine cannula.
Subsequently, the genes that are expressed in these endometrial cells are analyzed and the result is compared with a pattern of expression of these same genes in the window of implantation according to a mathematical model. In this way, it is possible to determine whether the patient's endometrium is receptive or non-receptive.
When we obtain a 'non-receptive' result, depending on the diagnostic probability indicated by the experts who have performed the genetic study, a second biopsy will be recommended on another day of the cycle in order to determine, on an individualized basis, the best time to transfer the embryos.