A balanced or balanced chromosomal mutation such as a reciprocal translocation is a rearrangement without gain or loss of genetic material. However, parents carrying some type of these balanced mutations are at risk of fertility problems such as repeated miscarriage.
The 4 situations that can happen when having offspring with a balanced reciprocal translocation are the following:
- Having a healthy child, without the translocation.
- Having a healthy child, but who has inherited the balanced translocation. Therefore, you would also have future problems having children.
- Having a sick child because of inheriting an unbalanced translocation that affects an important gene.
- Having a spontaneous abortion due to genetic alterations in the fetus that are not compatible with life.
Read the full article on: What are recurrent miscarriages? – Causes, diagnosis and treatment ( 86).
By Ricardo Celís García M.D., M.Sc. (gynecologist), Gorka Barrenetxea Ziarrusta M.D., Ph.D. (gynecologist), Joel G. Brasch M.D. (gynecologist), Marta Barranquero Gómez B.Sc., M.Sc. (embryologist), Zaira Salvador B.Sc., M.Sc. (embryologist) and Cristina Algarra Goosman B.Sc., M.Sc. (psychologist).
Last Update: 04/06/2022
