The decision of when to transfer embryos, whether at day 3 of development or day 5, will depend on the situation of each patient. In both cases, there are advantages and disadvantages.
Among the benefits of transferring embryos at the blastocyst stage and, therefore, at day 5 of development is a better natural selection of the embryo. Chromosomally altered embryos will not be able to reach day 5.
Another advantage of embryo transfer at day 5 of embryo development is that it allows a better selection of the embryo taking into account the morphological characteristics. In addition, synchronisation with the endometrium is greater.
Blastocyst transfer also increases the rate of single transfers, which reduces the possibility of multiple pregnancy.