BrudyFertilAOX: the antioxidant that promotes fertility

By (gynecologist), (embryologist), (embryologist) and (psychologist).
Last Update: 02/10/2022

Oxidative stress is increasingly being linked to the increased rate of infertility in our society.

Therefore, a diet rich in antioxidants or even dietary supplements with these substances can be beneficial when seeking pregnancy.

BrudyFertilAOX is one of these nutritional supplements indicated for both men and women. This food supplement has several compounds with antioxidative action in its chemical composition, which will help to reduce oxidative stress.

What is oxidative stress?

Cellular oxidative stress is an increase of oxidizing agents (free radicals) within the cell, above levels that the cell can neutralize. This results in premature aging of the cell and an alteration of its functions.

A stressed cell is less able to do its job properly, as it becomes oxidized and inflamed. This occurs in all cells in the body that are subjected to oxidative stress, including eggs and sperm.

Our current lifestyle favors oxidative stress. A diet deficient in nutrients, a stressful lifestyle, lack of sleep, smoking, and alcohol are clear generators of free radicals that hinder reproduction.

Thus, when the female follicular fluid and the male seminal fluid are low in antioxidants, fertilization becomes more difficult, either naturally or by assisted reproduction techniques.

What is BrudyFertilAOX and how does it improve fertility?

BrudyFertilAOX is a DHA-based nutritional supplement. It is a fatty acid of the Omega-3 family, presented in the form of triglyceride (the most assimilable form of DHA and as it is present in breast milk) of high content (>70% of the total fatty acids). In addition, BrudyFertilAOX contains vitamins and minerals that promote reproduction.

BrudyFertilAOX is indicated in the following situations:

  • Strengthen the quality of semen and follicular fluid while preparing for pregnancy.
  • Couples who have encountered difficulties and have already undergone Assisted Reproduction processes, since they increase the probabilities of success of the treatment.

In addition, BrudyFertilAOX is a suitable supplement for men who want to freeze their sperm. This antioxidant will preserve the semen in better conditions, since it increases the fluidity of the sperm membrane. This is essential for a good freezing/thawing process.

What are the functions of antioxidants?

The purpose of antioxidants is to reduce or prevent oxidation and aging of cells. In addition, these molecules also favor sperm quality, since if there are large amounts of reactive oxygen species (ROS) in the semen, it could lead to a decrease in sperm quality:

If you wish to continue reading more in-depth information, you can visit the following article: What are antioxidants and how do they affect semen quality?

Fatty acids

DHA is one of the major fatty acids in the cell membrane of spermatozoa and a major cellular antioxidant for both men and women.

Unfortunately, the current diet is deficient in this fatty acid, as it is mainly found in oily fish, and consumption of oily fish has decreased drastically in recent years, even in the Mediterranean diet. Therefore, its supplementation makes special sense when you want to improve both male and female reproduction.

Assisted procreation, as any other medical treatment, requires that you rely on the professionalism of the doctors and staff of the clinic you choose. Obviously, each clinic is different. Get now your Fertility Report, which will select several clinics for you out of the pool of clinics that meet our strict quality criteria. Moreover, it will offer you a comparison between the fees and conditions each clinic offers in order for you to make a well informed choice.

Studies show that DHA reduces oxidative sperm DNA fragmentation to absolutely normal levels.

Minerals

In addition to DHA, BrudyFertilAOX is fortified with minerals, such as zinc, which in men, contributes to the maintenance of normal testosterone levels, and is necessary for the maturation and formation of spermatozoa. Taken together with folic acid, it increases the number of spermatozoa, while in women it is a mineral necessary for ovulation and fertilization.

It also contains selenium, which improves the mobility, concentration and morphology of spermatozoa and, in women, protects the reproductive system from oxidative damage. Its deficiency has been linked to infertility, and low plasma selenium levels during early pregnancy have been associated with low birth weight. It is essential for the egg maturation process.

Vitamins

BrudyFertilAOX contains several B vitamins, such as folic acid, which in men improves sperm concentration and contributes to maintaining low homocysteine levels, whose presence in seminal plasma is related to poorer embryo quality in IVF processes, and in women, folic acid improves the environment for egg maturation.

Another of its components are vitamins C and E, which when taken together have been shown to protect the integrity of sperm DNA and, in women, create an antioxidant environment in the ovary, helping to protect follicular cells. On the other hand, vitamin E helps balance sex hormones and promotes endometrial circulation and receptivity.

When and how to take BrudyFertilAOX?

BrudyFertilAOX is a very complete nutritional supplement to promote fertility in both men and women.

Supplementation is recommended for both partners for at least three months, or until pregnancy is achieved, at a dosage of 3 capsules daily.

FAQs from users

Can male infertility be cured with BrudyFertilAOX?

By Lidia Pérez García M.D., M.Sc. (gynecologist).

BRUDYFERTY AOX is a vitamin supplement used to reduce oxidative stress, which can have consequences on sperm DNA. This vitamin supplement contains DHA, among other elements, and has an antioxidant effect.

Small randomized studies have shown the antioxidant effect of DHA supplementation in relation to a decrease in sperm DNA single-stranded fragmentation.

In the evolution of this damage there are factors that can be modified, such as eliminating smoking, alcoholism, obesity, treating seminal infections, limiting testicular overheating, avoiding the ingestion of oxidants and including in the diet the ingestion of antioxidant systems in the regular diet.
Read more

Can you increase sperm count?

By Zaira Salvador B.Sc., M.Sc. (embryologist).

Yes, as long as the male testicles are functional and there is sperm production. There are nutritional supplements that can help improve sperm production, such as vitamin complexes and antioxidants that reduce the damage caused by free radicals to spermatozoa.
Read more

Can male infertility be cured with diet?

By Zaira Salvador B.Sc., M.Sc. (embryologist).

A balanced diet, rich in antioxidants such as vitamin supplements or omega 3, can boost sperm quality in certain cases. However, improvement is not possible in the most severe cases of infertility. In such cases, fertility treatments are the only solution to achieve pregnancy. The following post may be of interest: Foods to boost sperm quality.

In the following post you will find more tips to improve semen quality and male fertility: Sperm quality: how to measure it and what to do to improve it

We make a great effort to provide you with the highest quality information.

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References

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Gual-Frau J, Abad C, Amengual MJ, Hannaoui N, Checa MA, Ribas-Maynou J, Lozano I, Nikolaou A, Benet J, García-Peiró A, Prats J. Oral antioxidant treatment partly improves integrity of human sperm DNA in infertile grade I varicocele patients. Hum Fertil (Camb). 2015 Sep;18(3):225-9.

Gülçin I. Antioxidant and antiradical activities of L-carnitine. Life Sci. 2006 Jan 18;78(8):803-11.

Gürbüz B, Yalti S, Fiçicioğlu C, Zehir K. Relationship between semen quality and seminal plasma total carnitine in infertile men. J Obstet Gynaecol. 2003 Nov;23(6):653-6.

Haseen Ahmed SD, Ahsan S, Iqbal T, Ahmed Burney SI. Relationship of seminal free L-Carnitine with functional spermatozoal characteristics: Results from an observational study conducted in a tertiary care hospital of Karachi, Pakistan. J Pak Med Assoc. 2017 Feb;67(2):280-284.

Lenzi A, Lombardo F, Sgrò P, Salacone P, Caponecchia L, Dondero F, Gandini L. Use of carnitine therapy in selected cases of male factor infertility: a double-blind crossover trial. Fertil Steril. 2003 Feb;79(2):292-300.

Lenzi A, Sgrò P, Salacone P, Paoli D, Gilio B, Lombardo F, Santulli M, Agarwal A, Gandini L. A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia. Fertil Steril. 2004 Jun;81(6):1578-84.

Li K, Li W, Huang Y. Determination of free L-carnitine in human seminal plasma by high performance liquid chromatography with pre-column ultraviolet derivatization and its clinical application in male infertility. Clin Chim Acta. 2007 Mar;378(1-2):159-63.

Lombardo F, Sansone A, Romanelli F, Paoli D, Gandini L, Lenzi A. The role of antioxidant therapy in the treatment of male infertility: an overview. Asian J Androl. 2011 Sep;13(5):690-7.

Majzoub A, Agarwal A. Systematic review of antioxidant types and doses in male infertility: Benefits on semen parameters, advanced sperm function, assisted reproduction and live-birth rate. Arab J Urol. 2018 Jan 2;16(1):113-124.

Matalliotakis I, Koumantaki Y, Evageliou A, Matalliotakis G, Goumenou A, Koumantakis E. L-carnitine levels in the seminal plasma of fertile and infertile men: correlation with sperm quality. Int J Fertil Womens Med. 2000 May-Jun;45(3):236-40.

Menchini-Fabris GF, Canale D, Izzo PL, Olivieri L, Bartelloni M. Free L-carnitine in human semen: its variability in different andrologic pathologies. Fertil Steril. 1984 Aug;42(2):263-7.

Nazari L, Salehpour S, Hosseini S, Allameh F, Jahanmardi F, Azizi E, Ghodssi-Ghassemabadi R, Hashemi T. Effect of antioxidant supplementation containing L-carnitine on semen parameters: a prospective interventional study. JBRA Assist Reprod. 2021 Feb 2;25(1):76-80.

Sheikh N, Goodarzi M, Bab Al-Havaejee H, Safari M, Amiri I, Najafi R, Hadeie J. L-carnitine level in seminal plasma of fertile and infertile men. J Res Health Sci. 2007 Jul 28;7(1):43-8.

Zöpfgen A, Priem F, Sudhoff F, Jung K, Lenk S, Loening SA, Sinha P. Relationship between semen quality and the seminal plasma components carnitine, alpha-glucosidase, fructose, citrate and granulocyte elastase in infertile men compared with a normal population. Hum Reprod. 2000 Apr;15(4):840-5.

FAQs from users: 'Can male infertility be cured with BrudyFertilAOX?', 'Can you increase sperm count?' and 'Can male infertility be cured with diet?'.

Read more

Authors and contributors

 Lidia Pérez García
Lidia Pérez García
M.D., M.Sc.
Gynecologist
Dr. Lidia Pérez has a degree in Medicine and a Master's Degree in Human Reproduction from the Complutense University of Madrid. More information about Lidia Pérez García
License: 282870961
 Marta Barranquero Gómez
Marta Barranquero Gómez
B.Sc., M.Sc.
Embryologist
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH). More information about Marta Barranquero Gómez
License: 3316-CV
 Zaira Salvador
Zaira Salvador
B.Sc., M.Sc.
Embryologist
Bachelor's Degree in Biotechnology from the Technical University of Valencia (UPV). Biotechnology Degree from the National University of Ireland en Galway (NUIG) and embryologist specializing in Assisted Reproduction, with a Master's Degree in Biotechnology of Human Reproduction from the University of Valencia (UV) and the Valencian Infertility Institute (IVI) More information about Zaira Salvador
License: 3185-CV
Adapted into english by:
 Cristina  Algarra Goosman
Cristina Algarra Goosman
B.Sc., M.Sc.
Psychologist
Graduated in Psychology by the University of Valencia (UV) and specialized in Clinical Psychology by the European University Center and specific training in Infertility: Legal, Medical and Psychosocial Aspects by University of Valencia (UV) and ADEIT.
More information about Cristina Algarra Goosman
Member number: CV16874

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