What Is the Average Cost of IVF In the USA?

By BSc, MSc, PhD (senior clinical embryologist), (gynecologist), (gynecologist), BSc, MSc (embryologist) and (invitra staff).
Last Update: 06/17/2020

In vitro fertilization (IVF) is one of the assisted reproduction treatments with a higher cost due to its complexity, technology and hormonal medication required to carry it out.

However, the price of IVF can vary greatly depending on the fertility clinic and various parameters such as the following: necessary complementary techniques, freezing of left-over embryos, use of donor gametes, etc

Therefore, it is essential that all patients who are about to undergo IVF study the budget provided by the clinic and know more accurately what in vitro fertilization may cost.

How much is IVF?

Currently, the price of in vitro fertilization is situated around $10,000-15,000 in the U.S.

As we have said, this price depends greatly on the assisted reproduction clinic and the services included in the initial budget.

In general, all IVF treatments include the following steps:

Hormonal medication is almost never included in this budget, as prices vary greatly depending on the drug and the indication of each patient. Therefore, to the cost of IVF, we have to add some $3,500-$5,000 more for fertility medication.

What makes the treatment more expensive?

Undoubtedly, the main reasons why IVF treatment ends up being more expensive than originally budgeted for are the diagnostic tests and complementary techniques required to optimize the process.

These are applied or not depending on each case and its indications. However, patients should be aware that the more tests and complementary techniques used, the greater the IVF success rates will be.

Diagnostic testing

Knowing the causes of infertility is essential to determine the most appropriate assisted reproduction treatment to achieve pregnancy.

Depending on the center, the first consultation of the couple may cost between $200 and $400. Ultrasound, blood tests, and semen analysis are charged extra and each of the tests may cost from as little as $100 to as much as $500.

However, sometimes it is not enough to perform a semen analysis, an ultrasound scan for women, and the respective hormone analyses.

There are more complex diagnostic tests to find out the exact reason for the infertility and to be able to more closely approximate the strategy to be followed. However, these tests have an additional cost that patients should know:

Karyotype
This is an analysis of the chromosomes and their structure to detect possible alterations. Its average price is situated at $11,000.
Hysteroscopy
is a test to visualize the inside of the uterus and detect possible malformations or lesions in the endometrium. Without surgery, hysteroscopy can cost between $700 and $3,500.
ERA testing
is an endometrial receptivity test. It consists of obtaining a sample of the endometrium by means of a biopsy and analysing its characteristics to find out whether or not it is receptive. It is usually charged with $850.
Sperm FISH
This is a genetic analysis of the spermatozoa specifically and costs approximately $380 on average.
Sperm DNA fragmentation test
is a test to evaluate the quality of sperm DNA and is part of the advanced semen analysis that costs between $290 (out-of-pocket) and $580 (insurance list price).
Testicular biopsy
When it is not possible to obtain sperm from semen, testicular tissue is biopsied. The cost of a testicular biopsy range from $2,500 to $5,600.
Thrombophilia testing
is indicated in cases of implantation failure and repeated miscarriages.
Sperm antibody study
also for cases of implantation failure and recurrent abortion.

Before carrying out any of these tests, it is very important to be well informed and ask about possible insurance coverage, fertility financing, or discount programs.

Complementary techniques

As far as the complementary techniques of IVF are concerned, we will explain what they consist of and what their approximate cost is below:

Blastocyst culture
the embryo transfer can be done with 3 or 5 day old embryos. The more evolved they are, the greater the implanting potential, but this has also an added cost.
Time-Lapse embryo culture
it is an incubator with a built-in camera that allows evaluating the embryos in all its stages since a video of all its development is obtained. However, this method adds up to the overall costs of IVF.
Sperm selection
spermatozoa for fertilization are usually selected by capacitation or by observation under the microscope in the case of ICSI. However, there are other additional techniques that allow a better selection, but that have an added cost: MACS, IMSI, PICSI, etc.
Assisted Hatching
consists of making a hole in the zona pellucida of the embryos to facilitate their exit and implantation. The technique costs about 200 euros, although it depends mainly on the number of embryos to be drilled.
Embryo vitrification
freezing of embryos for preservation is usually necessary for almost all IVF cycles, as it is common for there to be surplus embryos that are not transferred. Being able to vitrify them for future attempts allows the process to be optimized so that the woman does not have to go through ovarian stimulation and puncture. Its cost is at approximately $6,000-$20,000.

As you can see, the cost of IVF is usually not what is initially specified in the budget, but all the tests and techniques required for each type of patient must be added together.

Gamete donation and genetic studies

In addition to all the complementary techniques mentioned, there are other factors or requirements that make in vitro fertilization treatment much more expensive.

We refer to gamete donation and preimplantation genetic diagnosis (PGD).

When a man or woman cannot use their own sperm or eggs to have children, they will have to resort to assisted reproduction treatments with a gamete donor and this comes at an additional price:

IVF with donor sperm
with an additional cost from $200 to $3,000, sperm donation does not usually make IVF treatment very expensive.
IVF with egg donor
A wide range of prices can be found here that are more expensive than IVF, as the cost of egg donation depends on many factors. However, the approximate price may increase to $30,0000 per cycle.
IVF with embryo donation
if a woman or couple needs embryo donation, the price of this treatment will be between approximately $5,000 and $7,000.

As for PGD, this embryo genetics testing costs another $4,000 to $10,0000 so the final price of IVF with PGD can result in $20,000-$25,000.

If you need to undergo IVF to become a mother, we recommend that you generate your Fertility Report now. In 3 simple steps, it will show you a list of clinics that fit your preferences and meet our strict quality criteria. Moreover, you will receive a report via email with useful tips to visit a fertility clinic for the first time.

Price of IVF with frozen eggs

IVF with frozen or vitrified eggs is a variant of IVF using eggs that the woman has frozen in the past.

The reasons may be different, either because the patient went through cancer treatment or because she wanted to postpone motherhood and decided to preserve her fertility.

When this patient wants to become pregnant using these eggs, they must be thawed and fertilized to create the embryos. The cost of the whole process can be around $7,000 to $12,000 and doesn't include medication or storage.

As can be seen, this price is cheaper than that of IVF because the patient does not have to undergo ovarian stimulation and follicular puncture, as these were done in the past.

Costs of frozen embryo transfer

Similarly, if patients have frozen embryos from another IVF cycle it is not necessary to go through the whole process again to make a new embryo transfer.

The treatment consists of preparing the woman's endometrium and, at the most appropriate time, thawing the embryo or embryos for transfer.

This procedure is charged with $3,000 - $5,000 on average and usually includes endometrial growth controls, embryo diversification, and embryo transfer.

Get more information here: Frozen Embryo Transfer.

FAQs from users

How much does an IVF cycle cost?

By Sara Salgado BSc, MSc (embryologist).

This depends on the necessities of each patient. If in vitro fertilization is performed without sperm or egg donation the cost in the U.S. is between $10,000 and $15,000 to which you have to add up costs for medication which can make for another $5,000.

How much does a fertility treatment with egg donation cost?

By Sara Salgado BSc, MSc (embryologist).

In order to use donor eggs, in vitro fertilization is necessary. Provided no sperm donor is required, an egg donation IVF costs between $25,000 to $30,000 in the U.S.

How much is artificial insemination in the U.S.?

By Sara Salgado BSc, MSc (embryologist).

In the United States, the average price of an artificial insemination treatment with the partner's sperm is about $800. If donor sperm is needed it will be about 500-600 euros higher.

Suggested for you

If you are interested in knowing in detail the prices of other fertility treatments, I recommend you to continue reading the following article: Overview of the Main Costs of Fertility Treatments.

The cost of the techniques is a determining factor when choosing a fertility clinic. If you want to know what other factors are important and what you have to take into account, read on here: How Do I Choose the Right Fertility Clinic?

Our editors have made great efforts to create this content for you. By sharing this post, you are helping us to keep ourselves motivated to work even harder.

References

Collins SC, Xu X, Mak W. Cost-effectiveness of preimplantation genetic screening for women older than 37 undergoing in vitro fertilization. J Assist Reprod Genet. 2017 Nov;34(11):1515-1522.

Gunnala V, Schattman G. Oocyte vitrification for elective fertility preservation: the past, present, and future. Curr Opin Obstet Gynecol. 2017 Feb;29(1):59-63.

Moolenaar LM, Cissen M, de Bruin JP, Hompes PG, Repping S, van der Veen F, Mol BW. Cost-effectiveness of assisted conception for male subfertility. Reprod Biomed Online. 2015 Jun;30(6):659-66.

Pham CT, Karnon JD, Norman RJ, Mol BW. Cost-effectiveness modelling of IVF in couples with unexplained infertility. Reprod Biomed Online. 2018 Nov;37(5):555-563.

Simopoulou M, Sfakianoudis K, Antoniou N, Maziotis E, Rapani A, Bakas P, Anifandis G, Kalampokas T, Bolaris S, Pantou A, Pantos K, Koutsilieris M. Making IVF more effective through the evolution of prediction models: is prognosis the missing piece of the puzzle? Syst Biol Reprod Med. 2018 Oct;64(5):305-323.

Teoh PJ, Maheshwari A. Low-cost in vitro fertilization: current insights. Int J Womens Health. 2014 Aug 21;6:817-27.

Graphic material provided by Ovoclinic Madrid.

Verywellfamiliy: How much Does IVF Really Cost? Written by Rachel Gurevich, Last Update on March 05, 2020. Source.

FAQs from users: 'How much does an IVF cycle cost?', 'How much does a fertility treatment with egg donation cost?' and 'How much is artificial insemination in the U.S.?'.

Read more

Authors and contributors

 José Luis de Pablo
José Luis de Pablo
BSc, MSc, PhD
Senior Clinical Embryologist
Double Degree in Biology and Biochemistry from the University of Navarra. Master’s Degree about the Theoretical Basis and Laboratory Procedures in Assisted Reproduction from the University of Valencia (UV). Senior Clinical Embryologist from the ESHRE and ASEBIR Certification in Clinical Embryology. More than 15 years of experience as the director of IVF labs. More information about José Luis de Pablo
Dr. Mónica  Aura Masip
Dr. Mónica Aura Masip
Gynecologist
Dr. Mónica Aura has a degree in Medicine and General Surgery from the Autonomous University of Barcelona (UAB). She is also a specialist in Gynecology and Obstetrics from the Hospital de Santa Creu y Sant Pau and has a Master's degree in Human Assisted Reproduction from the University Juan Carlos I of Madrid and another in Health Center Management from the UB. More information about Dr. Mónica Aura Masip
Licence number: 31588
Dra. Rut Gómez de Segura
Dra. Rut Gómez de Segura
Gynecologist
Graduation in Medicine and Surgery from the University of Alcalá de Henares. Specialization in Obstetrics and Gynecology at the Hospital Costa del Sol in Marbella. Dr Rut Gómez de Segura currently works as medical director in the fertility center ProcreaTec in Madrid. More information about Dra. Rut Gómez de Segura
Licence number: 28/2908776
 Zaira Salvador
Zaira Salvador
BSc, MSc
Embryologist
Bachelor's Degree in Biotechnology from the Technical University of Valencia (UPV). Biotechnology Degree from the National University of Ireland en Galway (NUIG) and embryologist specializing in Assisted Reproduction, with a Master's Degree in Biotechnology of Human Reproduction from the University of Valencia (UV) and the Valencian Infertility Institute (IVI) More information about Zaira Salvador
License: 3185-CV
Adapted into english by:
 Romina Packan
Romina Packan
inviTRA Staff
Editor and translator for the English and German edition of inviTRA. More information about Romina Packan

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