What Are the Disadvantages of In Vitro Fertilization (IVF)?

By BSc, MSc (embryologist) and BA, MA (fertility counselor).
Last Update: 05/09/2014

Problems associated with in vitro fertilisation may be due to ovarian stimulation or pregnancy.

Below you have an index with the 3 points we are going to deal with in this article.

Ovarian stimulation

Risks derived from ovarian stimulation include:

  • Ovarian hyperstimulation syndrome
  • Multiple births: in cycles where two embryos are transferred, chances for a twin pregnancy are 6%. In cycles where three embryos are transferred, chances for a twin pregnancy are 6% and chances for a triplet pregnancy are 3%.

Ectopic pregnancy


Risks derived from pregnancy include:

  • Miscarriage: it is estimated to occur in between 20-22% of the cases, being more common during early pregnancy.
  • Ectopic pregnancy: according to statistics, 2 or 5 women out of every 100 women undergoing in vitro fertilisation may have an ectopic pregnancy. In natural conception, its probability may reach 1% up to 1.5%.

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 Neus Ferrando Gilabert
Neus Ferrando Gilabert
BSc, MSc
Bachelor's Degree in Biology from the University of Valencia (UV). Postgraduate Course in Biotechnology of Human Assisted Reproduction from the Miguel Hernández University of Elche (UMH). Experience managing Embryology and Andrology Labs at Centro Médico Manzanera (Logroño, Spain). More information about Neus Ferrando Gilabert
Adapted into english by:
 Sandra Fernández
Sandra Fernández
Fertility Counselor
Bachelor of Arts in Translation and Interpreting (English, Spanish, Catalan, German) from the University of Valencia (UV) and Heriot-Watt University, Riccarton Campus (Edinburgh, UK). Postgraduate Course in Legal Translation from the University of Valencia. Specialist in Medical Translation, with several years of experience in the field of Assisted Reproduction. More information about Sandra Fernández

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