Gonal-f is a medicine used in artificial insemination, conventional IVF and ICSI during ovulation induction.

The reported side effects are:

In women

Very common disorders (more than 10% of patients):

  • Injection site reactions (e.g. pain, erythema, haematoma, swelling and/or irritation at the site of injection).
  • Headache.
  • Ovarian cysts.

Common disorders (between 1% and 10% of patients):

  • Abdominal pain and gastrointestinal symptoms such as nausea, vomiting, abdominal discomfort, abdominal distension and diarrhoea.
  • Mild or moderate Ovarian Hyperstimulation Syndrome (OHSS, including associated symptomatology).

Discomfort caused by Gonal-f

Uncommon disorders (between 0.1% and 1% of patients): Severe OHSS (including associated symptomatology).

Rare disorders (between 0.01% and 0.1% of patients): Complication of severe OHSS.

Very rare disorders (less than 0.01% of patients):

    • Mild to severe hypersensitivity reactions including anaphylactic reactions and shock.
    • Thromboembolism, usually associated with severe OHSS.
    • Exacerbation or aggravation of asthma.

Gonal-f is expected to have no or negligible influence on the ability to drive and use machines.

In men

Very common disorders (more than 10% of patients): Injection site reactions (e.g. pain, erythema, haematoma, swelling and/or irritation at the site of injection).
Common disorders (between 1% and 10% of patients):

Gonal-f is expected to have no or negligible influence on the ability to drive and use machines.

Source: European Medicines Agency

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