An embryo with no chromosomal alteration does not have more chances for implantation, since implantation depends on many other factors such as a great amount of fragments in the embryo’s cytoplasm occupying space and hindering embryo development, the incapability of breaking through the zona pellucida to implant, a slower-than-normal cleavage rate, when the endometrium is not prepared for implantation, etc.
In conclusion, an increased pregnancy rate has been noticed in women who are within the range of patients for whom this technique is indicated.
In women for whom PGD is not indicated, not only the pregnancy rate does not increase, but also it can even diminish, since handling an embryo can stop its development if it was not in good condition.
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