By Neus Ferrando Gilabert BSc, MSc (embryologist).
Last Update: 06/03/2014

Information about the embryo’s set of chromosomes can be obtained by means of a PGD. Thus, only genetically approved embryos will be loaded into the maternal uterus through embryo transfer.

For this reason, PGD is considered to increase the chances for embryo survival. If it had some kind of aneuploidy, in many cases it would be non-viable and therefore miscarriage would occur.

An embryo with no chromosomal alteration does not have more chances for implantation, since implantation depends on many other factors such as a great amount of fragments in the embryo’s cytoplasm occupying space and hindering embryo development, the incapability of breaking through the zona pellucida to implant, a slower-than-normal cleavage rate, when the endometrium is not prepared for implantation, etc.

Results of Pre-implantation Genetic Diagnosis

In conclusion, an increased pregnancy rate has been noticed in women who are within the range of patients for whom this technique is indicated.

In women for whom PGD is not indicated, not only the pregnancy rate does not increase, but also it can even diminish, since handling an embryo can stop its development if it was not in good condition.

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Authors and contributors

 Neus Ferrando Gilabert
BSc, MSc
Embryologist
Bachelor's Degree in Biology from the University of Valencia (UV). Postgraduate Course in Biotechnology of Human Assisted Reproduction from the Miguel Hernández University of Elche (UMH). Experience managing Embryology and Andrology Labs at Centro Médico Manzanera (Logroño, Spain). More information